Bringing Tissue Together.

Tissuelock is the world's first internal tissue plane device for head-to-toe surgery to bring tissue planes together, reducing surgical dead space and the need for drains or progressive tension sutures.

Our Technology

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Avoidable Provider Spend $3.3B Healthcare system burden from surgical wound closure complications, including seroma, hematoma, and infection.

Surgery creates dead space between tissue layers: skin, fat, and fascia. We made a device that closes the gaps.

Today, dead space is managed with drains and progressive tension sutures. Both cost patient comfort, operative time, and follow-up care, causing a 10% surgical complication rate.

Revolutionizing Soft Tissue Repair

Tissuelock reduces surgical dead space, which minimizes the need for drains and progressive tension sutures.

Tissuelock technology is designed to reduce swelling, minimize fluid accumulation, and improve patient recovery.

In The Surgical Field

How Tissuelock works

Tissuelock Spans The Reconstruction Continuum

Head-to-toe surgery applications

Our Technology

Plastic and Reconstructive Surgery

Reconstructive and cosmetic surgery of the abdomen, face and neck, and breast and extremities, including limb salvage.

General Surgery

Hernia repair, solid organ transplant, and gastrointestinal and colorectal resection.

Cardiothoracic Surgery and Neurosurgery

Procedures of the heart, brain, and spine, from aortic dissections to dural leaks.

Built By Leaders in Plastic Surgery

10+ decades

of combined surgical innovation and commercialization experience as clinicians, scientists, and operators at leading healthcare institutions.

Where We Are

Founded in St. Louis, for patients worldwide

Based in the Midwest's biomedical innovation heartland, St. Louis, home to Washington University School of Medicine, BJC Healthcare, and the Cortex Innovation District.

Map data © OpenStreetMap contributors, Esri

We want to hear from you.
Let's transform surgery together.

Tissuelock is a pre-clinical company.

connect@tissuelock.com

Drains are simply a workaround, not a solution.

Following large soft tissue repair and reconstructive procedures, patients go home with painful drains and a log book.

Surgeons accept the burden because the alternative, fluid collecting, in an open plane is worse.

Yet, it still happens: patients recover more poorly, and surgeons spend more time on follow-up care.

We discovered the upstream solution: reduce the dead space.

Tissuelock replaces

Surgical drains

Progressive tension sutures

Founding team

Grihith Varaday, BA Chief Executive Officer

Justin Sacks, MD, MBA, FACS Chief Medical Officer

Matthew Wood, PhD Chief Scientific Officer

Linda Elkins, MBA, MS Chief Operating Officer

Xiaowei Li, PhD Head, Scientific Advisory

We are guided by first principles to unlock a paradigm-shift in surgery

Evidence-based, patient-first

Every design decision starts with what is best for patients, validated with their insights alongside provider feedback.

Sustainable innovation

Transforming surgery is a marathon, not a sprint. We are focused on creating lasting change.

Determined, together

We are an interdisciplinary team, motivated to improve clinical outcomes at-scale.

Bringing Tissue Together.

Surgery creates dead space between tissue layers: skin, fat, and fascia. We made a device that closes the gaps.

Tissuelock reduces surgical dead space, which minimizes the need for drains and progressive tension sutures.

How Tissuelock works